High therapeutic activity potent low dose compounds require product handling in containment facilities, which provide the necessary protection for personnel, the environment and for the product itself. We have a small and large-scale suite for the production of HPAPIs. Our expertise and reputation in this highly specialized area has been recognized worldwide by customers and agencies alike across the US, Europe, and Japan. With over 20 years of experience handling highly potent molecules with an OEL down to 1 μg/m³, our highly skilled team has produced numerous HPAPI products ranging from grams to hundreds of kilograms.

Small Scale HPAPI Production Suite

  • Glovebox containment
  • Reactor Sizes: 100 & 250 L
  • Pressure: Up to 4 bar
  • Temperature: -80°C to 150°C
  • Product Isolation: 0.125 m² Hastelloy pressure-filter-dryer
  • Batch Sizes: Up to 10 kg / Batch

Large Scale HPAPI Production Suite

  • Reactor Size: 4000 L
  • Temperature: -10°C to 140 °C
  • Pressure: Up to 4 bar
  • Product Isolation: Hastelloy Pressure filter dryers (0.8 and 2.5 m² ) and Centrifuge
  • Batch Sizes: Tens to Hundreds kg / batch